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NSilico Delivers on Parallel Computing Solutions at PRACE-DAYS 2015

Brendan Lawlor, parallel computing specialist with NSilico delivered his talk on novel functional programming coupled with low level instruction based parallelism to an audience at PRACE DAYS 2015.This parallel technology helps drive bioinformatics processing in Simplicity™ our user friendly bioinformatics platform. The PRACE DAYS conference brought together experts from academia and industry who presented their advancements in HPC-supported science and engineering.
The programme included:

  • Invited keynotes
  • Scientific presentations in plenary & parallel sessions
  • The User Forum (UF) meeting PRACEdays15
  • Brendan’s talk was extremely well received, with commendation from the organisers.

Government reports warns of outbreak of drug resistant bacteria

A government forecast that as many as 80,000 people could die if there was an outbreak of a drug-resistant infection in Britain,. According to the report, about 200,000 people could fall victim to a bacterial blood infection if there was a widespread outbreak that existing antibiotics could not tackle. Even routine operations would become high-risk procedures and many elements of modern medicine, such as organ transplants, would be too dangerous, the report said. The numbers of infections complicated by antimicrobial resistance was expected to “increase markedly” over the next 20 years, it added. The report highlights the need for new technologies and methologies for understanding pathogens and how to best to combat them. 

Icelandic study reveals the genome of a entire nation.

The deCODE genetics team performed the research by combining DNA data of 10,000 people and combing it with family trees. They say that they could now find every woman at high-risk of breast cancer "at the touch of a button" and it would be "criminal" not to use the information.The study, published in the Nature Genetics, used the data to make a suite of discoveries including the age of the last common ancestor of men

100k Genomes project produces first diagnoses of rare diseases

Three men from two families are the first patients to be diagnosed with rare diseases after volunteering to have their complete genetic codes mapped as part of the groundbreaking 100,000 Genomes Project.They will now be eligible for personalised treatment designed to target their genetic defects or help future generations of their relatives.The men, all from the Newcastle area, are among 75,000 people being recruited to the £300m project who will have their genetic codes, or genomes, sequenced by scientists. Some will have more than one version of their genome sequenced, making up the 100,000 total.

ResearchKit – Apple’s medical research platform

ResearchKit is Apples newest innovation, a platform designed to help medical research, and not one that requires any extra hardware, or hard-to-understand software. It'll use iPhones, iPhone apps and a similar cloud data network we all use today. it will be used to collect and collate reams of data. This data might be inputted manually or automatically, depending on the app used. And where relevant, the data can be collated and used in wider research "We're incredibly confident that ResearchKit is going to transform medical research," said Apple CEO Tim Cook.

10X Genomics Unveils it’s new method to improve Illumina sequencing

At the Advances in Genome Biology and Technology conference in Florida, 10X Genomics has unveiled it’s new method for improved DNA sequencing. The company which raised $55.5 million in venture capital last month seeks to help geneticists prepare “long reads” of DNA that can be sequenced by Illumina sequencing platforms. Basically the company has created a new instrument called a GemCode which will prepare libraries for sequencing on Illumina machines. 

How DNA Sequencing could revolutionise the sewer system

As sequencing technology develops scientists are constantly devising new and interesting ways for it to improve our lives. In 2010 geneticist Eric Schadt had one idea that could revolutionise how we track disease outbreaks - Use DNA sequencing to examine raw sewage. The basic idea is simple, use some form of DNA sensor to detect pathogens in sewage and then track back the outbreaks to a specific town, or even street! We’re still a ways off actually implementing something like this, but given the pace that sequencing technology is developing it could be a lot closer than we think. Christopher Mason, a Weill Cornell Medical College professor, has already implemented a simpler version of the idea, applying swabs to surfaces all over New York City to create a “Pathomap” of germs that has already been published in cell.

Sepsis is on the rise, warns medical expert

The rise in antibiotic resistance is leading to a growing number of deaths from sepsis, experts warn. Deaths from sepsis are on the rise due to growing antibiotic resistance which means previously harmless infections can become fatal, a healthcare expert has warned. Mark Bellamy, president of the Intensive Care Society, said new antibiotics must be developed to prevent the spread of resistant bugs which can lead to sepsis.

NSilico will be showing Simplicity at BIBM workshop!

NSilico's Simplicity promises make life of geneticists much more easy. It takes genetic data and runs it against widely used tools to find genes and trim the data. Scientists also get a full report from it. And we will be at the Bioinformatics and Biomedicine Conference held in Belfast! Check out our workshop!


The world’s most easy-to-use tool for the management of raw-sequence data